So my early April deadline for announcing a new season of the show this year has passed. I would say that a fall run would be out of the question at this point. The only hope would be for ABC to include a sixth season as a mid-season filler, but an announcement would have to be made within the next few weeks at the latest.

In other news, TheFutonCritic.com had this to say about The Mole:

BROADCAST HISTORY:
1/9/01 - 8/11/08
STATUS:
canceled/ended (2007-2008 season)
TIME SLOT:
completed airing its current season
SEASON(S):
5 (45 episodes, 0 of which have yet to air)
ADDITIONAL NOTES:
confirmed as canceled on 4/8/09

I don't know where they got the "canceled on 4/8/09" part, since no news items exist confirming this (at least none that I've found). If any of you are curious and sleuthy enough, try searching for leads that might indicate that this is true.